Blar i NTNU Open på forfatter "Vornewald, Pia"

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    • BMP signaling in the intestinal epithelium drives a critical feedback loop to restrain IL-13-driven tuft cell hyperplasia 

      Lindholm, Håvard Takle; Parmar, Naveen; Drurey, Claire; Poveda, Marta Campillo; Vornewald, Pia; Ostrop, Jenny; Sanchez, Alberto Diez; Maizels M, Rick; Oudhoff, Menno (Peer reviewed; Journal article, 2022)
      Intestinal parasite infections or allergic reactions promote IL-13–induced differentiation of tuft cells as one manifestation of type 2 immunity in the gut. Using organoid cultures of intestinal epithelial cells, Lindholm ...

    • Smooth muscle-specific MMP17 (MT4-MMP) regulates the intestinal stem cell niche and regeneration after damage 

      Alonso, Mara Martin; Iqbal, Sharif; Vornewald, Pia; Lindholm, Håvard Takle; Damen, Mirjam J.; Martínez, Fernando; Hoel, Sigrid; Sanchez, Alberto Diez; Altelaar, Maarten; Katajisto, Pekka; Arroyo, Alicia G.; Oudhoff, Menno (Peer reviewed; Journal article, 2021)
      Smooth muscle is an essential component of the intestine, both to maintain its structure and produce peristaltic and segmentation movements. However, very little is known about other putative roles that smooth muscle cells ...